Vet Guide

Acute Oral Toxicities to Cats

Table 2

Generic Name (ActiveTrade Namea) LD50 of Active Ingredient (mg/kg)b Usual % Active Ingredient in Bait Quantity of Bait to Give LD50 in 2 kg (4.4 lb) Cat Source of Data for LD50 Info (see Endnotes)
brodifacoum (d-Con®, Final®, Havoc®, Jaguar®, Ratak®, Talon®-G, Weatherblok®XT) 25 0.005c 1,000 g (35.3 oz) 3, 5, 20
bromadiolone (BootHill®, Brigand™, Contrac®, Hawk®, JustOneBite®, Kaput®Doom, Maki®,Ratimor®, Ratoxin®, Resolv®, Revolver™) 25d 0.005 1,000 g (35.3 oz) 1
chlorophacinone (A-CFormula 90™, Borderline™, Rozol®) unknown 0.005 - -
difenacoum (Di-Kill®, Multi-Kill®, Sorexa™) 100 0.005 4,000 g (141.0 oz) 19
difethialone (BlueMax™, d-Con®, FastDraw®, FirstStrike®, Generation®, Hombre™) >16 0.0025 1,280 g (45.2 oz) 25
diphacinone (Ditrac®, Kaput®-D, Ramik®, TomCat®) 5-15 15 0.005 200 g (7.1 oz) to 600 g (21.2 oz) 6, 9, 23 3
warfarin (Kaput®, Rodex™) 5-50e 6-40 200-300 2.5 - 20 0.025 20 g (0.71 oz) to 2,400 g (84.7 oz) 7, 10 20 9 16

Table 2 Footnotes

a. See trade names for additional information regarding trademark ownership and affiliation.

b. Bold values LD50 range used in calculating ‘Quantity of Bait to Give LD50 in 2 kg Cat.’

c. This active ingredient is also available in .0025 (2,000 g to reach LD50 in 2 kg cat.)

d. This figure is actually the maximum tolerated oral dosage (MTD).

e. Cats are generally regarded as being as susceptible as dogs to warfarin. The range of LD50 may be partly explained by increased susceptibility to poisoning during estrus (Spencer, 1950).

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